Quorum Sensing and Antimicrobial Resistance in Bacteria

Authors

  • Noor Riyadh Almzil Ministry of Higher Education and Scientific Research, Baghdad, Iraq.

DOI:

https://doi.org/10.51699/cajmns.v7i4.3355

Keywords:

Autoinducers, Quorum-sensing, LuxR, LuxI, Acyl homoserine lactone

Abstract

is the process of modifying gene expression in reaction to changes within the population of cells density. Gene expression is impacted by an autoinducer's minimal threshold stimulatory dosage. Each Gram-positive and Gram-negative bacterium employs quorum sensing signaling circuits to regulate various kinds of biological functions. Acylated homoserine lactones are frequently by bacteria that are gram-negative as autoinducers. Another means of communication involving microorganisms that are Gram-positive and Gram-negative is through processed oligo-peptides. According to current study, autoinducer-mediated cell-cell interaction occurs both inside and as well as amongst bacterium species, growing proof that bacterial autoinducers cause distinct reactions in their hosts. Bacteria are able to coordinate gene expression through mutual interaction, although the target genes, signal relay systems, and chemical signals mediated by bacterial quorum sensing systems differ, and so the collective response of society in any given circumstance. Therefore, one of the earliest steps toward multi-cellularity may have been the emergence of quorum sensing systems in bacteria. We will review in this article the mechanism of both quorum sensing and Autoinducers and explain the role of both gram negative and negative bacteria according to their transcription factor and the advantage that they have been effect on life.

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Published

2026-07-24

How to Cite

Almzil , N. R. . (2026). Quorum Sensing and Antimicrobial Resistance in Bacteria. Central Asian Journal of Medical and Natural Science, 7(4), 113–124. https://doi.org/10.51699/cajmns.v7i4.3355

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