Blood Homocysteine Level and its Prognostic Value in Pregnant Women with Preeclampsia
Keywords:
preeclampsia, endothelial dysfunction, hyperhomocysteinemia
Abstract
Hypertensive conditions still occupy one of the leading places among maternal and perinatal morbidity and mortality. The study is devoted to determining the level of homocysteine in a normal pregnancy, as well as in preeclampsia.
The purpose of this study was to study the course of pregnancy and assess the state of newborns, from mothers with various severity of preeclampsia, depending on the level of homocysteine. Analyzed the state of 49 pregnant women with preeclampsia and their newborns. The control group was 20 pregnant women without hypertensive disorders. Preeclampsia and the level hyperhomocysteinemia statistically significantly affects not only the health of pregnant women, but also the state of health of the newborn
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2. Adizova D.R. Ocenka effektivnosti ingibitora angiotenzin-prevrashchayushchego fermenta enalaprila u bol'nyh arterial'noj gipertenziej na urovne pervichnogo zvena zdravoohraneniya // Vrach-aspirant. - 2007. - № 6. - S. 462-464..
3. Amonov I.I, Ashurova N.G, Adizova S.R. Ob osobennostyah reproduktivnoj sistemy mnogorozhavshih zhenshchin s anemiej i pielonefritom // Nauka molodyh –Eruditio Juvenium, №4, 2015.
4. Alekseeva L.L. Techenie i iskhody beremennosti pri preeklampsii//Vrach-aspirant. - 2017. - T. 81. № 2.2. - S. 261-267.
5. Adizova S.R., Ihtiyarova G.A. Morfologicheskaya harakteristika placenty u zhenshchin s preeklampsiej. // Novyj den' v medicine, S. 26-30 2020
6. Ayupova F.M., Ihtiyarova G.A., Nigmatova G.M. Faktory riska perinatal'nyh oslozhnenij po dannym retrospektivnogo analiza// ZH Pediatriya Tashkent, 2019. –S 224-229
7. Kattahodzhaeva M.H., Gajbullaeva D.F. Pokazateli endotelial'noj disfunkcii i markery sistemnogo vospaleniya u beremennyh pri preeklampsii//RE-HEALTH journal №2.2(6)2020
8. Kuzina E. A., Tyurina E.P. Iskhody rodorazresheniya i sostoyanie novorozhdennyh u beremennyh zhenshchin s preeklampsiej//Simvol nauki. -2015. - № 6. - S. 311-313.
9. Kulida L. V. Smirnova E. V., Panova I. A. Kliniko-anamnesticheskie dannye i patomorfologicheskie osobennosti placent pri zaderzhke rosta ploda u zhenshchin s hronicheskoj arterial'noj gipertenziej i prisoedinivshejsya preeklampsiej// Rossijskij vestnik akushera-ginekologa. – 2016. - №16(5). – S. 66-70
10. Merkushkina T.I., Tyurina E.P. Techenie i iskhody beremennosti u zhenshchin s preeklampsiej//Nauchnaya mysl'.- 2018. - № 2-4. - S. 46-53.
11. Pogorelova T.N., Gun'ko V.O., Linde V.A. Proteomnyj profil' placenty pri fiziologicheskoj beremennosti i beremennosti, oslozhnennoj preeklampsiej//Akusherstvo i ginekologiya. - 2013. - № 7. - S. 24-29.
12. Ihtiyarova G.A., Adizova S.R. «Prognocticheckaya cennoct' citokinov u zhenshchin pri oclozhnennyh rodah c preeklampciej» New day in medicine 3(27)2019 c 117-119
13. Tulabaeva G.M., Adizova D.R., Talipova Y.S., Cagatova X.M. Efficiency of L-arginine intreatment of coronary heart disease in older women. O‘zbekiston terapiya axborotnomasi. 2013; 2:32-36.
14. Rakhmatova D. B. Analysis of the risk factors of Chd in persons over 60 years among the population of the city of Bukhara //Asian studies. Индия. – 2019. – Т. 1. – С. 33-38.
15. Hlestova G.V., Karapetyan A.O., SHakaya M.N., Romanov A.YU., Baev O.R. Materinskie i perinatal'nye iskhody pri rannej i pozdnej preeklampsii// Akusherstvo i ginekologiya. - 2017. - № 6.- S.41-47ACOG. First-trimester risk assessment for early-onset preeclampsia //Obstetrics and Gynecology, 2015; Vol. 126. pp 25-27.
16. Aita K. et al. Acute and transient podocyte loss and proteinuria in preeclampsia // Nephron. Clin. Pract, 2019; Vol. 112, N 2. pp. 65-70.
17. Alnaes-Katjavivi, P., Roald, B., Staff, A.C. Uteroplacental acute atherosis in preeclamptic pregnancies: Rates and clinical outcomes differ by tissue collection methods//Pregnancy Hypertension, 2020;19, pp. 11-17
18. Jim B., Jean-Louis P., Qipo A., Garry D., Mian S., Matos T. et al. Podocyturia as a diagnostic marker for preeclampsia amongst high-risk pregnant patients. J. Pregnancy. 2018; 2012:984630.
19. Karthikeyan V.J., Lip G.Y. Endothelial damage/dysfunction and hypertension in pregnancy. Front. Biosci. (Elite Ed). 2019 Jun 1; 3: 1100-8.
20. Lazdam M., Davis E.F., Lewandowski A.J., Worton S.A. et al. Prevention of Vascular Dysfunction after Preeclampsia: A Potential Long-Term Outcome Measure and an Emerging Goal for Treatment. Journal of Pregnancy.2012, Article ID 704146, 8 p.
Published
2022-09-05
How to Cite
Rizokulovna , A. S. (2022). Blood Homocysteine Level and its Prognostic Value in Pregnant Women with Preeclampsia. Central Asian Journal of Medical and Natural Science, 3(5), 51-57. Retrieved from https://cajmns.casjournal.org/index.php/CAJMNS/article/view/1046
Section
Articles
