Synthesis of complex compounds of Iron (II) ions with quercetin in different environments and evaluation of their stability constants
Abstract
In the article, complex compounds of iron (II) ions with quercetin were synthesized in different environments and their stability constants were determined. According to it, the values of the stability constants of the complex formed from Fe(II) cations and quercetin in different environments (pH) were evaluated.
References
Батраков В. В., Абросимова Е. Е., Блинцова Н. В. Особенности строения, свойств и биологической активности флаваноидов //Актуальные проблемы экспериментальной и клинической медицины. – 2016. – С. 285-285.
Carullo G., Cappello, A. R., Frattaruolo, L., Badolato, M., Armentano, B., Aiello, F. (2017). Quercetin and derivatives: useful tools in inflammation and pain management //Future medicinal chemistry. – 2017. – V. 9. – №. 1. – P. 79-93.
Hirpara K. V. Aggarwal, P., Mukherjee, A. J., Joshi, N., Burman, A. C. Quercetin and its derivatives: synthesis, pharmacological uses with special emphasis on anti-tumor properties and prodrug with enhanced bioavailability //Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents). – 2009. – V. 9. – №. 2. – P. 138-161.
. Jomova K., Valko M. Advances in metal-induced oxidative stress and human disease //Toxicology. – 2011. – V. 283. – №. 2-3. – P. 65-87.
. Valko M., Morris H., Cronin M. T. D. Metals, toxicity and oxidative stress //Current medicinal chemistry. – 2005. – V. 12. – №. 10. – P. 1161-1208.
. Ismatov D.M., Arzimurodova H., Mukhamadiyev A.N., Mukhamadiyev N.Q., Uzokov J.R. Quantum chemical evaluation of a complex compound of quercetin flavonoid with Fe (II) ions // Scientific Bulletin. Natural Science Series (Chemistry, Biology, Geography). - 2022. - V. 131. – N 1. - P. 46-49.
Arzimurodova X., Ismatov D. M., Uzokov J. R., Mukhamadiyev A. N., Mukhamadiev N. Q., Fattoyeva N. H. Quantum chemical evaluation of complex formation of Co (II) ions with quercetin molecule //Central Asian Journal of Medical and Natural Science. – 2022. – V. 3. – №. 3. – P. 338-344.
Ismatov D. M., Mukhamadiyev N. Q. Synthesis of quersetin complex compounds with iron (II) ions assessment of its stability //Central Asian Journal of Medical and Natural Science. – 2022. – V. 3. – №. 3. – P. 329-337.
Ismatov D. M., Mirzakhadjayeva, L., Toshmatova, R. V., Mukhamadiyev, N. Q. Sectrophotometrical evaluation of the stability of melanine complex with Cu (II) ion //Central Asian Journal of Medical and Natural Science. – 2022. – V. 3. – №. 3. – P. 325-328.
Qin X. R. , Zhang, M. J., Gao, X. N., Lin, Y., Li, M. A., Si-Yi, H. E. Study on the antibacterial activity of quercetin //Chemistry & Bioengineering. – 2009. – V. 26. – №. 4. – P. 55-57.
Tan J., Zhu L., Wang B. DNA binding and cleavage activity of quercetin nickel (II) complex //Dalton Transactions. – 2009. – №. 24. – P. 4722-4728.
. Akhmadi S.M., Dekhgan G., Hosseinpurfeyzi M.A., Dolatabadi JEN and Kashanyan S. Preparation, characterization and DNA-binding of the water-soluble quercetin-molybdenum (VI) complex // DNA and Cell Biology. – 2011. – V. 30. – №. 7. – P. 517-523.
Torreggiani, A., Tamba, M., Trinkero, A., and Bonora, S. Copper(II)–quercetin complexes in aqueous solutions: spectroscopic and kinetic properties // Journal of Molecular Structure. – 2005. – V. 744. – P. 759-766.
Raza, A., Xu, X., Xia, L., Xia, C., Tang, J., & Ouyang, Z. Quercetin-iron complex: synthesis, characterization, antioxidant, DNA binding, DNA cleavage, and antibacterial activity studies //Journal of fluorescence. – 2016. – V. 26. – №. 6. – P. 2023-2031.
Vlasova I.V., Zheleznova T.Yu., Vershinin V.I. Choice of model solutions for spectrophotometric assessment of the stability of complex compounds using the method of isomolar series // Vestnik. Omsk University. - 2012.- №2. - P. 127-130.
Stolpovskaya E. V., Trofimova N. N., Babkin V. A., Khutsishvili S. S., Zhitov R. G., Chuparina E. V., Maltsev A. S. Research and optimization of the complex formation reaction of manganese ions (II) with dihydroquercetin in the aquatic environment // Chemistry of vegetable raw materials. – 2020. – №. 3. – P. 47-56.
Stolpovskaya E. V., Trofimova N. N., Babkin V. A., Zhitov R. G. Research and optimization of the reaction of complex formation of cobalt ions with dihydroquercetin in an aqueous medium // Chemistry of plant raw materials. – 2019. – №. 1. – P. 95–104.
Trofimova N. N., Babkin V. A., Vakulskaya T., Chuparina E. V. Study of methods of synthesis, structure and properties of complexes of flavonoids with metal ions. Message 1. Synthesis and determination of the structure of complexes and salts of dihydroquercetin with zinc, copper (II) and calcium in aqueous solutions // Chemistry of vegetable raw materials. – 2012. – №. 2. – P. 51-62.
Trofimova N. N., Stolpovskaya E. V., Babkin V. A. Study of methods of synthesis, structure and properties of complexes of flavonoids with metal ions. Message 2. Optimization of the reaction of complex formation of zinc with dihydroquercetin in the aquatic environment // Chemistry of vegetable raw materials. – 2013. – №. 3. – P. 91-97.
. Stolpovskaya E. V., Trofimova N. N., Babkin V. A. Study of methods of synthesis, structure and properties of complexes of flavonoids with metal ions. Message 4. Study of the reaction of complex formation of Ca2+ ions with dihydroquercetin // Chemistry of vegetable raw materials. – 2014. – №. 4. – P. 125-130.
Xu D., Hu, M. J., Wang, Y. Q., Cui, Y. L. Antioxidant activities of quercetin and its complexes for medicinal application //Molecules. – 2019. – V. 24. – №. 6. – P. 1123.
Papan P. , Kantapan, J., Sangthong, P., Meepowpan, P., Dechsupa, N. Iron (III)-Quercetin Complex: Synthesis, physicochemical characterization, and MRI cell tracking toward potential applications in regenerative medicine //Contrast Media & Molecular Imaging. – 2020. – V. 2020. – P. 1-22.
Kuntic V., Blagojevic, S., Malesev, D., Radovic, Z., Bogavac, M. Spectrophotometric investigation of the Pd (II)-quercetin complex in 50% ethanol //Monatshefte für Chemie. – 1998. – V. 129. – №. 1. – P. 41-48.
Ryan P., Hynes M. J. The kinetics and mechanisms of the reactions of iron (III) with quercetin and morin //Journal of inorganic biochemistry. – 2008. – V. 102. – №. 1. – P. 127-136.
