Optimization of the Treatment of Pelvic Pain in Endometriosis

Authors

  • Ahmedova Nilufar Maxmudjonovna Andizhan State Medical Institute
  • Kamildjanova Gulmira Isroiljon qizi Andizhan State Medical Institute

DOI:

https://doi.org/10.51699/cajmns.v2i6.530

Keywords:

external genital endometriosis, chronic pelvic pain, gonadotropin-releasing hormone antagonists, gonadotropin-releasing hormone agonists

Abstract

Gonadotropin-releasing hormone (GnRh), which provides a higher level of regulation of reproductive function, is released by the hypothalamus and binds to the GnRH receptors in the pituitary gland, leading to the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

References

1. Jones A.V., Hockley J.R., Hyde C., Gorman D. et al. Genome-wide association analysis of pain severity in dysmennorhea identifies association at chromosome 1p13.2, near the nerve growth factor locus. Pain. 2016 Nov., 157 (11): 2571–2581.
2. Chiantera V. Abesadze E. Mechsner S. How to understand the complexity of endometriosis-related pain. J Endometr Pelvic Pain Disord. 2017; 9 (1): 30–38.
3. Buck Louis G.M., Hediger M.L., Peterson C.M., Croughan M., Sundaram R., Stanford J. et al. Incidence of endometriosis by study population and diagnostic method: the ENDO study. Fertil Steril. 2011;96: 360–5.
4. Manero M.G., Alcazar J.L. Interleykin-8 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis. Fertil. Steril. 2011; 92: 2: 450–452.
5. Acs N., O'Brien C., Jiang P. et al. Treatment of endometriosis-associated pain with elagolix, an oral GnRH antagonist: results from a phase 2, randomized controlled study. J Endometriosis. 2015; 7: 56–62.
6. Howard F.M. Endometriosis and mechanisms of pelvic pain. J.Minim. Invasive Gynecol. 2009; 16 (5): 540–550. 26.
7. Orazov M. R., Chayka A.V., Nosenko E.N. Dienogest v lechenii hronicheskoy tazovoy boli pri adenomioze. Medikosocіal'nі problemi sіm'ї. 2013; 18: 3: 49–54. [in Russian ]
8. Orazov M.R. Immunniy gomeostaz perifericheskoy krovi u zhenshin s bolevym sindromom adenomioza. Trudniy pacient. 2014; 12: 12: 39–44. [in Russian]
9. Orazov M.R. Osobennosti endokrinnogo balansa u zhenshin s bolevym sindromom adenomioza. Trudny pacient. 2014; 12: 8–9: 10–13. [in Russian]
10. Chopin N., Ballester M., Borghese B., Fauconnier A., Foulot H.,Malartic C., Chapron C.. Relation between severity of dysmenorrhea and endometrioma. Acta. Obstet. Gynecol. Scand. 2006; 85(11): 1375–1380.
11. Orazov M.R. Nekotorye gisteroskopicheskie kriterii diagnostiki tazovoy boli, obuslovlennoy adenomiozom. Trudny pacient. 2013; 11: 8–9: 10–13. [in Russian]

Downloads

Published

2021-12-25

How to Cite

Maxmudjonovna, A. N. ., & qizi, K. G. I. . (2021). Optimization of the Treatment of Pelvic Pain in Endometriosis. Central Asian Journal of Medical and Natural Science, 2(6), 436–438. https://doi.org/10.51699/cajmns.v2i6.530

Issue

Section

Articles