Clinical Characteristics of Early and Late Complications in Newborns Who Experienced Chronic Intrauterine Fetal Hypoxia

Ishniyazova Nadira  Durdibayevna; Salikhova Kamola  Shavkatovna; Agzamkhodjaeva Barno  Ulugbekovna; Abdurakhmanova Fatima  Rikhsibaevna; Ortikmatova Zilola  Kodirali kizi

doi:10.51699/cajmns.v7i3.3252

Authors

Ishniyazova Nadira Durdibayevna PhD, Associate Professor, Department of Neonatology, Tashkent State Medical University, 36 Bakhodira Street, Tashkent 100100, Uzbekistan
Salikhova Kamola Shavkatovna MD, PhD, DSc, Head of the Department of Neonatology, Republican Specialized Scientific and Practical Medical Center of Pediatrics, 3 Talant Avenue, Chimbay 2 Street, Tashkent 100179, Uzbekistan
Agzamkhodjaeva Barno Ulugbekovna PhD, Resident Physician, Republican Specialized Scientific and Practical Medical Center of Pediatrics, 8, 3-Oksoy Street, Tashkent 100042, Uzbekistan
Abdurakhmanova Fatima Rikhsibaevna PhD, Head of the Department of Nursing Care for Premature Newborns, Republican Specialized Scientific and Practical Medical Center of Pediatrics, 3 Talant Avenue, Chimbay 2 Street, Tashkent 100179, Uzbekistan
Ortikmatova Zilola Kodirali kizi Master’s Degree Student, Tashkent State Medical University, 27/29 Bogishamol Street, Tashkent 100100, Uzbekistan

DOI:

https://doi.org/10.51699/cajmns.v7i3.3252

Keywords:

chronic intrauterine hypoxia, newborns, neonatal complications, fetal hypoxia, neurodevelopment, respiratory distress, perinatal pathology

Abstract

Chronic intrauterine fetal hypoxia remains an important cause of neonatal morbidity and long-term developmental disturbances in modern perinatal medicine. The present study aimed to evaluate the clinical characteristics of early and late complications among newborns who experienced prolonged oxygen deficiency during intrauterine life. The investigation included newborn infants delivered from pregnancies complicated by chronic fetal hypoxia and assessed their respiratory adaptation, neurological condition, cardiovascular stability, feeding ability, and developmental outcomes during follow-up observation. The obtained findings demonstrated that respiratory distress syndrome, neurological depression, feeding difficulties, and muscle tone abnormalities were among the most frequent early complications detected after birth. During subsequent pediatric monitoring, several infants additionally developed delayed psychomotor adaptation, sleep disturbances, and neurobehavioral instability. The study confirms that chronic prenatal hypoxia may negatively influence both immediate neonatal adaptation and later neurodevelopmental maturation. Early diagnosis, prolonged pediatric observation, and timely rehabilitation interventions remain essential for improving clinical outcomes and reducing long-term complications in affected children.

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