Diabetes Mellitus Type 2 and Prediction Making Use of Big Data and Machine Learning Algorithms

Authors

  • Archana Jain Research Scholar, Department of Computer Science and Engineering, School of Engineering & Technology, IIMT University, India
  • Suraj Malik Associate Professor, Department of Computer Science and Engineering, School of Engineering & Technology, IIMT University, India
  • Akshay Raj Assistant Professor, Department of Research & Development, IIMT University, India

Keywords:

Diabetes Mellitus Type 2, Hyperglycaemia, Insulin Resistance, Early Prediction, Disease Prevention, Predictive Modelling, Big Data, Machine Learning

Abstract

In the 21st century, Diabetes Mellitus Type 2 is a major health problem in the world. It occurs due to persistent hyperglycaemia and insulin resistance. If the disease is predicted in its early stages, effective prevention and management can be achieved. In this paper, some current developments in predictive modelling based on Big data and Machine learning algorithms for Diabetes Mellitus Type 2 have been reviewed. It compares and analyses the work of various Machine Learning algorithms, outlines their potential and constraints, and points to their applications and future research in this field.  Recent studies (2022-2025) indicate that machine learning and deep learning models are better than traditional statistical models for risk stratification and early prediction. However, there are still issues with data quality, ethics, and model interpretability. The article provides suggestions for further research in the field of ethical Artificial Intelligence, the integration of multimodal data, and its application to real-world practice.

References

American Diabetes Association, “Standards of medical care in diabetes,” Diabetes Care, vol. 46, no. Suppl. 1, pp. S1–S280, 2023.

T. Chen and C. Guestrin, “XGBoost: A scalable tree boosting system,” in Proc. 22nd ACM SIGKDD Int. Conf. on Knowledge Discovery and Data Mining (KDD), San Francisco, CA, USA, 2016.

L. Floridi et al., “AI4People—An ethical framework for AI in society,” Philosophical Transactions of the Royal Society A, vol. 378, no. 2166, p. 20190361, 2020.

J. M. Forbes and M. E. Cooper, “Mechanisms of diabetic complications,” Physiological Reviews, vol. 93, no. 1, pp. 137–188, 2013.

D. S. Wankhede and R. Selvarani, “Dynamic architecture-based deep learning approach for glioblastoma brain tumor survival prediction,” Neuroscience Informatics, vol. 2, p. 100049, 2022.

D. S. Wankhede, “Analysis and prediction of soil nutrients (pH, N, P, K) for crop using machine learning classifier: A review,” in Innovations in Communication and Computing. Singapore: Springer, 2022, pp. 111–121.

M. Preetha, D. S. Wankhede, R. Kumar, G. Ezhilarasan, S. Khurana, and G. S. Sahoo, “Leveraging AI-driven systems to advance data science automation,” in Proc. 1st Int. Conf. Emerging Research in Computational Science (ICERCS), 2023.

D. S. Wankhede, V. Gaikwad, M. Karnik, S. Kapase, and O. Bakkam, “The decentralized smart contract certificate system utilizing Ethereum blockchain technology,” Procedia Computer Science, vol. 230, pp. 923–934, 2023.

K. Chitra, S. S. Priscila, E. S. Soji, R. Rajpriya, B. Gayathri, and A. Chitra, “Transforming electrical simulation and management with smart grid technologies,” International Journal of Engineering Systems Modelling and Simulation, vol. 16, no. 4, pp. 241–253, 2025.

M. V. Soosaimariyan, H. L. Allasi, K. Chitra, and J. B. Gnanadurai, “Enhanced EMG-based hand gesture recognition by using generalized deep infomax networks,” Journal of Sensors, vol. 2025, no. 1, p. 9496890, 2025.

K. Lakshmi and K. Chitra, “Stress Net: Multimodal stress detection using ECG and EEG signals,” Journal of Data Science, vol. 2024, no. 59, pp. 1–8, 2024.

S. Rishabh, K. Chitra, and C. S. Yap, “A study on non-fungible tokens marketplace for secure management,” INTI Journal, vol. 2024, no. 18, pp. 1–8, 2024.

S. Shreyash, S. Gaur, K. Chitra, and M. Y. N. Zuhaili, “EasyLearnify – A student study portal,” INTI Journal, vol. 2024, no. 17, pp. 1–6, 2024.

D. S. Wankhede, C. J. Shelke, V. K. Shrivastava, R. Achary, and S. N. Mohanty, “Brain tumor detection and classification using adjusted InceptionV3, AlexNet, VGG16, VGG19 with ResNet50–152 CNN model,” EAI Endorsed Trans. Pervasive Health Technol., vol. 10, Art. no. 6377, 2024.

D. S. Wankhede, C. J. Shelke, and A. George, “An enhanced algorithm for predicting IDH1 mutations and 1p19q mitigation in glioma tumor,” in AIP Conf. Proc., vol. 3217, no. 1, Art. no. 020025, 2024.

C. J. Shelke, D. S. Wankhede, P. M. Paul, V. K. Shrivastava, and R. Achary, “Enhanced prediction of glioma brain tumors using deep learning algorithm,” in AIP Conf. Proc., vol. 3217, no. 1, Art. no. 020022, 2024.

D. S. Wankhede, B. Karare, A. D. Warange, P. Bhokardankar, and K. S. Tidke, “Blockchain-enabled thyroid detection using voting classifier and deep convolutional neural network,” in Proc. 3rd Int. Conf. Networks and Advances in Computational Technologies (NetACT), 2025.

P. V. Deshmukh, A. K. Shahade, M. R. Shahade, D. S. Wankhede, and P. H. Gohatre, “Breast cancer detection using a novel hybrid machine learning approach,” Ingénierie des Systèmes d’Information, vol. 30, no. 3, Art. no. 301, 2025.

P. V. Deshmukh, A. K. Shahade, D. S. Wankhede, M. R. Shahade, N. N. Sakhare, and P. H. Gohatre, “Optimizing NLP processes with human insight and machine intelligence,” Ingénierie des Systèmes d’Information, vol. 30, no. 5, pp. 1339–1347, 2025.

Y. K. Reddy and K. Akhila, “Extended release matrix tablets of nateglinide: Formulation and in vitro evaluation,” Asian Journal of Pharmaceutical Research, vol. 10, no. 2, pp. 101–104, 2020.

S. H. Rasheed, M. Arief, P. S. Vani, S. R. Gajavalli, G. Venkateswarlu, K. S. Hussain, N. V. Kumar, and Y. K. Reddy, “Simultaneous estimation of rabeprazole sodium and itopride hydrochloride in capsule dosage form by UV spectrophotometry,” Research Journal of Pharmacy and Technology, vol. 4, no. 4, pp. 558–560, 2011.

D. M. Reddy, Y. K. Reddy, D. R. Reddy, N. V. Kumar, M. Suresh, M. Althaff, and N. K. Valaparla, “Formulation and evaluation of ciprofloxacin ocuserts,” Research Journal of Pharmacy and Technology, vol. 4, no. 11, pp. 1663–1665, 2011.

Y. K. Reddy and F. Tahseen, “Development and evaluation of gastroretentive floating tablets of nizatidine based on effervescent technology,” Research Journal of Pharmaceutical Dosage Forms and Technology, vol. 12, no. 2, pp. 93–97, 2020.

B. Lakshmikanth and T. Jesudas, "Influence of stainless steel short fibres as reinforcements in enhancing the performance of aluminium 7075 alloy matrix composites," Transactions of the Indian Institute of Metals, vol. 77, pp. 495–501, 2024.

T. Jesudas, S. Ramesh, and R. M. Arunachalam, "Prediction and optimization of micro EDM process parameter using multiple regression and artificial neural network," Elixir Mechanical Engineering, vol. 66, pp. 20895–20900, 2014.

M. R. Donthi, S. R. Munnangi, K. V. Krishna, R. N. Saha, G. Singhvi, and S. K. Dubey, “Nanoemulgel: A Novel Nano Carrier as a Tool for Topical Drug Delivery,” Pharmaceutics, vol. 15, no. 1, p. 164, Jan. 2023.

M. R. Donthi et al., “Formulating Ternary Inclusion Complex of Sorafenib Tosylate Using β-Cyclodextrin and Hydrophilic Polymers: Physicochemical Characterization and In Vitro Assessment,” AAPS PharmSciTech, vol. 23, no. 7, Oct. 2022.

M. R. Donthi, R. Dudhipala, R. Komalla, D. Suram, and N. Banala, “Open Access Preparation and Evaluation of Fixed Combination of Ketoprofen Enteric Coated and Famotidine Floating Mini Tablets by Single Unit Encapsulation System,” J Bioequiv Availab, vol. 7, no. 6, pp. 279–283, 2015.

D. Mahipalreddy, D. Narendar, K. Devendhar, S. Dinesh, A. S. Kiran, and B. Nagaraj, “Preparation and Evaluation of Ketoprofen Enteric Coated Mini Tablets for Prevention of Chronic Inflammatory Disease,” J. Pharm. Drug Deliv. Res., vol. 04, no. 02, 2015.

M. R. Donthi, R. N. Saha, G. Singhvi, and S. K. Dubey, “Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation,” Pharmaceutics, vol. 15, no. 3, p. 736, Mar. 2023.

M. R. Donthi, N. Dudipala, R. Komalla, and N. Banala, “Design and Evaluation of Floating Multi Unit Mini Tablets (MUMTS) Muco Adhesive Drug Delivery System of Famotidine to Treat Upper Gastro Intestinal Ulcers,” vol. 3, no. 5, p. 179, 2015.

D. K. Gupta, S. K. Sharma, P. K. Gaur, and A. P. Singh, “Lovastatin loaded solid lipid nanoparticles for transdermal delivery: In vitro characterization,” Res. J. Pharm. Technol., vol. 15, no. 3, pp. 1085–1089, 2022.

S. Mishra, S. K. Sharma, J. Yadav, and B. Kasana, “A review on how exactly diuretic drugs are working in our body,” J. Drug Deliv. Ther., vol. 3, no. 5, pp. 115–120, 2013.

J. Yadav, S. K. Sharma, and L. Singh, “Evaluation of antidepressant activity of leaves extract of Moringa oleifera using FST and TST model on Swiss albino mice,” World J. Pharm. Res., vol. 5, pp. 967–976, 2016.

S. Mishra, S. K. Sharma, A. Rizvi, and A. Chowdhary, “Physicochemical standardization and phytochemical screening of potential medicinal herb: Vetiveria zizanioides (roots),” Int. J. Phytother., vol. 1, pp. 1–6, 2014.

S. K. Somayajula, "Enterprise Data Migration Success Patterns: Lessons from Large-Scale Transformations," International Journal of Research in Computer Applications and Information Technology (IJRCAIT), vol. 8, no. 1, pp. 757-776, Jan.-Feb. 2025.

S. K. Somayajula, "Demystifying Modern Data Warehousing: From Traditional to Cloud-Native Solutions," International Journal of Scientific Research in Computer Science, Engineering and Information Technology, 2025.

S. K. Somayajula, "Building a Career in Enterprise Data Architecture: A Practical Guide," International Research Journal of Modernization in Engineering Technology and Science (IRJMETS), vol. 7, no. 1, Jan. 2025.

D. K. Arora et al., “An in vitro assessment of microleakage of pit and fissure sealants and restorative materials using dye penetration method,” Journal of Pharmacy and Bioallied Sciences, Feb. 2025.

R. Nagar et al., “In vitro analysis of compressive strength of three different aesthetic restorative materials,” Journal of Pharmacy and Bioallied Sciences, Feb. 2025.

N. Maiti et al., “Assessment of the efficacy of photobiomodulation (PBM) therapy in periodontal treatment: a longitudinal study,” Journal of Pharmacy and Bioallied Sciences, vol. 16, no. Suppl 3, pp. S2449–S2451, Jul. 2024.

S. K. Somayajula, "Advanced ETL Optimization: A Framework for Next-Generation Data Integration," International Journal of Computer Engineering and Technology (IJCET), vol. 16, no. 1, pp. 381-406, Jan.-Feb. 2025.

S. Somayajula and A. Orlovsky, "Proof, Truth and Contradiction in the System and Meta-System: Comprehensive Mathematical Solutions and Implementation Framework," 2025.

S. Dhanalakshmi, T. Jesudas, and M. Pradeep Kumar, "A stir casting process-based experimental analysis of the wear properties of an Al 6063 alloy reinforced with ceramic particles," Romanian Journal of Materials, vol. 55, no. 2, pp. 107–120, 2025.

M. Chugh and S. Vyas, “Digital Twin: A Promising New Era for Elderly Healthcare,” in Digital Twins for Sustainable Healthcare in the Metaverse, IGI Global Scientific Publishing, 2025, pp. 55–76.

S. Vyas, M. Chugh, and S. Gupta, “Comprehensive study of digital forensics in contemporary domain,” in AIP Conference Proceedings, vol. 2916, no. 1, AIP Publishing, 2023.

S. Gupta and S. Vyas, “Contemporary role of edge-AI in IoT and IoE in healthcare and digital marketing,” in Edge-AI in Healthcare, CRC Press, 2023, pp. 75–84.

S. Gupta, M. Chugh, and S. Vyas, “Understanding immersive technologies for autism detection: A study,” Automation and Computation, pp. 364–370, 2023.

M. Chugh and S. Vyas, “Exploring the incredible potential and opportunity of the metaverse world,” in Strategies and Opportunities for Technology in the Metaverse World, IGI Global, 2023, pp. 34–47.

S. Gupta, M. Chugh, and S. Vyas, “A Study on AI-Empowered Smart Healthcare: Key Challenges and Opportunities,” in Proc. Int. Conf. Smart Systems and Advanced Computing, Cham: Springer Nature Switzerland, 2022, pp. 255–266.

S. Vyas, S. Gupta, and M. Chugh, “Metaverse Technologies and Applications: A Study,” in Proc. Int. Conf. Cybersecurity in Emerging Digital Era, Singapore: Springer Nature Singapore, 2022, pp. 287–300.

M. Chugh, A. Pandey, and S. Vyas, “A Comprehensive Study on the Association Between Personality Traits and Software Development,” in Proc. 4th Int. Conf. Information Management & Machine Intelligence, 2022, pp. 1–6.

R. Boina, “Assessing the Increasing Rate of Parkinson’s Disease in the US and its Prevention Techniques”,” International Journal of Biotechnology Research and Development, vol. 3, no. 1, pp. 1–18, 2022.

M. Chugh, S. Gupta, and S. Vyas, “Leveraging the Potentiality of Blockchain Technology for Waste Management in Smart City Development,” in Proc. Int. Conf. Information and Management Engineering, Singapore: Springer Nature Singapore, 2022, pp. 377–387.

S. Gupta, M. Chugh, and S. Vyas, “A Study on AI-Empowered Smart Healthcare: Key Challenges and Opportunities,” in Proc. Int. Conf. Smart Systems and Advanced Computing, Cham: Springer Nature Switzerland, 2022, pp. 255–266.

J. Dineshkumar and T. Jesudas, "Hybrid polymer matrix development using cashew nut shell liquid as an additive into epoxy resin," Journal of the Chinese Institute of Engineers, vol. 46, no. 4, pp. 380–388, 2023.

M. Pradeepkumar, T. Jesudas, C. Sasikumar, and M. Narasimharajan, "Evolutionary optimization of wire EDM process for the surface finish on a magnesium AZ91D alloy using an ANN and a genetic algorithm," Materials and Technology, vol. 58, no. 5, pp. 663–669, 2024.

R. Kumari, R. K. Singh, N. Kumar, and R. Kumari, “Preparation of superfine Bael leaf nanopowder, physical properties measurements and its antimicrobial activities,” Egypt. Chem. Bull., vol. 12, no. 4, pp. 284–297, 2023.

M. K. Sinha, R. Kumari, and A. Kumar, “Ameliorative effect of Ganoderma lucidum on sodium arsenite induced toxicity in Charles Foster rats,” J. Adv. Zool., vol. 45, no. 5, 2024.

Downloads

Published

2026-04-04

How to Cite

Jain, A., Suraj Malik, & Akshay Raj. (2026). Diabetes Mellitus Type 2 and Prediction Making Use of Big Data and Machine Learning Algorithms. Central Asian Journal of Medical and Natural Science, 7(2), 476–484. Retrieved from https://cajmns.casjournal.org/index.php/CAJMNS/article/view/3187

Issue

Section

Articles