Multidrug-Resistant Acinetobacter baumannii Isolated from Clinical Samples in Al-Najaf City, Iraq

Anfal Abdulhussain Jawad

doi:10.51699/cajmns.v7i2.3182

Authors

Anfal Abdulhussain Jawad Department of Microbiology, Faculty of Medicine, Jabir Ibn Hayyan University for Medical and Pharmaceutical Researches, Najaf, Iraq

DOI:

https://doi.org/10.51699/cajmns.v7i2.3182

Keywords:

Acinetobacter baumannii, Antimicrobial Susceptibility, Multi-Drug Resistance, ICU

Abstract

Acinetobacter baumannii has emerged as a major cause of opportunistic pathogens associated with hospital-acquired infections and multidrug resistance worldwide. The currwnt study aimed to determine the antimicrobial susceptibility patterns of Acinetobacter baumannii isolated from different clinical samples at Al-Najaf city, Iraq. A cross-sectional study was conducted over a six-month period (March to September 2024). A total of 25 clinical isolates A. baumannii were obtained from various clinical specimens. Antimicrobial susceptibility testing was conducted using minimum inhibitory concentration (MIC) methods using the VITEK-2 automated system according to standard guidelines. Statistical analysis was performed using SPSS software, with a p-value ≤ 0.05 was considered statistically significant. Females revealed a slightly higher infection rate (56%) than males (44%). Sputum were the most common source of isolation (32%), followed by urine (28%) and blood samples (20%). A high resistance levels were observed against ceftazidime (80%), cefotaxime (72%), and imipenem (68%). Colistin showed the highest sensitivity rate (92%) with highly significant difference (P=0.0001). The study showed a high prevalence of multidrug-resistant Acinetobacter baumannii particularly in intensive care units settings. Colistin remains the most effective antimicrobial agent. Continuous surveillance and effective antibiotic stewardship are needed to limit the spread of resistant strains.

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