The Evaluation of Inflammatory and Cardiometabolic Markers in Obese Patients Before and After Bariatric Surgery

Waleed Mohammed  Ali; Dler Omar  Mohammed; Hazim Sadiq  Ahmed

doi:10.51699/cajmns.v7i2.3124

Authors

Waleed Mohammed Ali Kirkuk Teaching Hospital, Kirkuk Directory of Health, Kirkuk, Iraq
Dler Omar Mohammed Department of General Surgery, College of Medicine, University of Kirkuk, Kirkuk, Iraq
Hazim Sadiq Ahmed General and Laparoscopic Surgery Department, Kirkuk Teaching Hospital, Kirkuk Directory of Health, Kirkuk, Iraq

DOI:

https://doi.org/10.51699/cajmns.v7i2.3124

Keywords:

Obesity, Inflammatory Markers, Cardiometabolic, Bariatric Surgery

Abstract

Background: Obesity is a major health issue in the world, with many chronic illnesses, such as cardiovascular disease and type 2 diabetes, being attributed to it. It is principally accompanied by systemic inflammation, which worsens these conditions. The effects of bariatric surgery on the inflammatory and cardiometabolic markers are not fully studied; nonetheless, the effect of bariatric surgery on obesity is proven to be effective. Aim of the Study: It will be an evaluation of change in the inflammatory and cardiometabolic parameters of the patient who undergoes bariatric surgery, based on the parameters, i.e., Endocane, Hscrp, lipid profiles, and blood pressure. Patients and Methods: The study involved 20 obese individuals (BMI [?]30kg/m2) who were to undergo bariatric surgery. The preoperative and three and six-month post-surgery cardiometabolic profiles and Blood samples were taken. The research was a measurement of inflammatory markers (CRP, Endocane) and cardiometabolic markers (lipid profile, glucose levels, and blood pressure). There was a statistical analysis, which compared the pre- and post-surgery values. Results: A major decrease was seen in the inflammatory markers (CRP, Endocan). Cardiometabolic health was also improved, and the BMI, fasting glucose, blood pressure, and triglycerides also dropped. There was an increase in insulin sensitivity, and the lipid profiles were improved with an improvement in the HDL cholesterol. Conclusion: Bariatric surgery has a great effect on the inflammatory markers and cardiometabolic markers of obese patients. Such results can be used to advocate the role of bariatric surgery in relation to weight reduction as well as decreasing the risk of obesity-related comorbidities. The long-term effects should be checked in further research.

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