GC-MS Analysis of Essential Oil Isolated from Mediasia Macrophylla Pimen Plants

Nayimova Bahora; Mukhamadiev  Abdukodir; Mukhamadiev  Nurali; Fazliyeva  Nigina; Dusov  Tursunmurod; Radjabov  Asatillo; Kulmirzayeva  Sabina

doi:10.51699/cajmns.v7i1.3040

Nayimova Bahora Samarkand State University named after Sharof Rashidov, Uzbekistan
Mukhamadiev Abdukodir Samarkand State University named after Sharof Rashidov, Uzbekistan
Mukhamadiev Nurali Samarkand State University named after Sharof Rashidov, Uzbekistan
Fazliyeva Nigina Samarkand State University named after Sharof Rashidov, Uzbekistan
Dusov Tursunmurod Samarkand State University named after Sharof Rashidov, Uzbekistan
Radjabov Asatillo Samarkand State University named after Sharof Rashidov, Uzbekistan
Kulmirzayeva Sabina Samarkand State University named after Sharof Rashidov, Uzbekistan

DOI: https://doi.org/10.51699/cajmns.v7i1.3040

Keywords: essential oil, Mediasia macrophylla, GC MS analysis, methyleugenol, ligustilide, phenylpropanoids, bioactive compounds

Abstract

Mediasia macrophylla Pimen, a forthcoming source of bioactive substances, has not been sufficiently investigated, and this study reveals the chemical composition of its essential oil. There is little prior research for this genus, indicating a knowledge gap regarding its chemical and functional characteristics. To our knowledge, this is the first comprehensive laboratory study of the chemical composition of this essential oil, which was isolated by hydrodistillation and subsequently analyzed by GC-MS.

Twenty five compounds was found in the extraction, with methyleugenol as the major component (46.28%) followed by trans ligustilide (11.66%) and geranyl acetate (7.45%). The highest percentage of oil was made up of phenylpropanoids, esters, terpenes, phenols and lactones. Chiral properties were demonstrated by several components, implying that isomeric differences might impact both aroma and biological activities. The present results provide the first in depth chemical characterization of the essential oilof the species while also revealing the presence of compounds with established antimicrobial, antioxidant and anti-inflammatory activity.

Therefore, these results indicate strong applications in the field of pharmaceuticals, cosmetics and aromatherapy. Collection from Account Track Macro This initial study addresses an important gap by documenting the chemical diversity of the essential oil of M. macrophylla and lays the groundwork for future studies focused on the chemical, pharmacological, and enantiomeric composition of M. macrophylla essential oil.

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