A Study on Microwave Preparation and Stability of Some Organic Reagent Derivatives of 2- (2,3 Dimethyl Phenylamino) Benzoic Acid in Light and Darkness

Maan Ziadan Khalaf

doi:10.51699/cajmns.v6i4.2960

Authors

Maan Ziadan Khalaf Salah al-Din Education Directorate, Iraq

DOI:

https://doi.org/10.51699/cajmns.v6i4.2960

Keywords:

Green reaction, Microwave, Stability, Triazole, Thiazolidinone

Abstract

Microwave-assisted chemistry has attracted much interest as a new tool in green chemistry with regard to its efficiency, energy saving, and environmental friendliness. Separating the present invention is known to increase the speed of organic synthesis, providing tremendous benefits over the old-fashioned techniques. The use of microwave irradiation as an alternative to classical heating methods for the synthesis of organic derivatives has received increasing attention in particular the synthesis of substituted and derivatives of 2-(2,3 dimethyl phenylamino) benzoic acid which are important for their pharmaceutical applications due to a wide range of biological activity. Microwave-assisted synthesis has been demonstrated to be an efficient method for improving the reaction process, however, the stability of these compounds in different conditions, especially under light and dark, have not yet been investigated. Moreover, this gap in knowledge restricts the generalisation of these methods to industrial processes. Abstract: In this study, we derive organic reagents from 2-(2,3 dimethyl phenylamino) benzoic acid under microwave radiation which are both stable in solution and high performing over a range of environmental conditions. The compounds were synthesized from the solvents free, green method, and then characterization was done using UV-Vis, IR, and NMR spectroscopy. Reagent stability was also evaluated, demonstrating a high stability of reagents in the light and dark with some compounds exhibiting increased stability from the effect of a blocking group. It fills important informational gaps in the literature and provides new details on the stability and environmental behavior of organic reagents that are synthesized by microwave. The results highlight microwave-assisted methods as effective, scalable synthetic techniques for generating organic compounds that are thermally stable and produced in high yields, with important implications for sustainable chemical processes in research and industry.

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