Analysis of Gallbladder Stones by X-ray Fluorescence

  • Mustafa Safaa Abdul Jabbar Saeed Department of Medical Devices Engineering Technology, Al-Hussain University College, Iraq
  • Zaid Mohammed Abd Zaid Jomea Department of Medical Devices Engineering Technology, Al-Hussain University College, Iraq
  • Ahmed Yahea Jassim Mohammed Department of Medical Devices Engineering Technology, Nothern Technical University College, Technical College of Engineering, Iraq
  • Ruaa Abdullah Yousif Neama Department of Medical Devices Engineering Technology, Hillah University College, Iraq
Keywords: Gallstones, Gallbladder, X-ray fluorescence (XRF), Elemental analysis, Cholesterol, Calcium carbonate

Abstract

Gallstone disease impacts millions globally. Over the decades  modern techniques have been applied in laminar. Nevertheless, the fundamental cause of its  formation has continued to be a topic of speculation. The current analysis of present sunshine  utilizes various methods, including infrared. Through FTIR spectroscopy, we investigated the role of  cholesterol, bilirubin, and calcium carbonate in gallstone formation within the gallbladder. Our  experimental findings indicated that cholesterol, whether alone or in conjunction with bilirubin and  calcium carbonate, is the predominant component of human gallstones and serves as the  primary cause of gallstone formation. Gallstone samples were identified using WDXRF. Some of the  interiors exhibited tones of pebbles in various colors, while the outer casing was brown and black. FTIR  analyses are presented, along with WD-XRF analyses and other findings related to gallstone samples.  This clearly demonstrates that calcium and copper constitute the salts of bilirubin's to a greater extent than  the brown and black coloration of the central part of gallstones

References

Beckhoff, B., Kanngießer, B., Langhoff, N., Wedell, R., & Wolff, H. (2007). Handbook of practical X-ray fluorescence analysis (pp. 411–432). Springer.

Shackley, M. (2010). X-ray fluorescence spectrometry (XRF) in geoarchaeology (pp. 7–44). Springer.

Thomas, H. (1995). Root formation. International Journal of Developmental Biology, 39, 231–237.

Robinson, J., Frame, E., & Frame, G. (2004). Undergraduate instrumental analysis (6th ed., pp. 449, 535). Taylor & Francis.

Smith, L. H. (1989). Journal of Urology Part 2, 141, 707.

Daniel, R. T., Renal, B., Benitz, I. O., Sharbaugh, D. M., Whipps, S., & Khan, S. R. (2006). Langmuir, 22, 2450.

Sheng, X., Ward, M. D., & Wesson, J. A. (2003). Journal of the American Chemical Society, 125, 2854.

Finlayson, B. (1974). Urologic Clinics of North America, 1, 181.

Ansari, M. S., Gupta, N. P., Hemal, A. K., Dogra, P. N., Seth, A., Aron, M., & Singh, T. P. (2005). International Journal of Urology, 12, 12.

Carson, P. J., & Brewster, D. R. (2003). Journal of Paediatrics and Child Health, 39, 325.

Herring, L. C. (1962). Journal of Urology, 88, 545.

Terai, A., Okada, Y., Ohkawa, T., Ogawa, O., & Yoshida, O. (2000). International Journal of Urology, 7, 452.

Mandel, N. S., & Mandel, C. S. (1989). Journal of Urology, 142, 1516.

Daudon, M., Doshimoni, R., Hennequin, C., Fellahi, S., Le Moel, G., Paris, M., Troupel, S., & Lacour, B. (1995). Urological Research, 23, 319.

Menon, M., Parulkar, B. G., & Drach, G. W. (1997). Campbell’s urology (7th ed., Vol. 3, p. 2661). Philadelphia: Harcourt Brace and Co.

Trotman-Dickenson, A. F. (1996). Principles of X-ray spectrometry. Springer Science & Business Media.

Pak, C. Y. C., & Resnick, M. I. (2001). Medical and surgical management of kidney and gallstones. In F. L. Coe, M. J. Favus, C. Y. C. Pak, J. H. Parks, & G. M. Preminger (Eds.), Kidney stones: Medical and surgical management. Lippincott-Raven Publishers.

Liu, Y., Wang, W., Zhang, J., & Xie, Q. (2015). Composition of gallstones and risk factors for gallstone disease: A prospective study. Hepatobiliary & Pancreatic Diseases International, 14(2), 189–196.

Boyce, A. J., & Manning, D. A. (2011). A simple X-ray fluorescence technique for the determination of trace elements in geological and biological samples. Journal of Analytical Atomic Spectrometry, 26(4), 823–830.

Portincasa, P., Moschetta, A., & Palasciano, G. (2006). Cholesterol gallstone disease. The Lancet, 368(9531), 230–239.

Sharma, M., Rathi, S., & Pathak, R. (2019). Fourier transform infrared spectroscopy (FTIR) analysis of gallstones: A study on patients from North India. Journal of Clinical and Diagnostic Research, 13(6), BC01–BC04.

Kratzer, W., Mason, R. A., & Kächele, V. (1999). Gallstone prevalence in the United States. Gastroenterology, 117(3), 632–639.

Published
2025-09-04
How to Cite
Saeed, M. S. A. J., Jomea, Z. M. A. Z., Mohammed, A. Y. J., & Neama, R. A. Y. (2025). Analysis of Gallbladder Stones by X-ray Fluorescence. Central Asian Journal of Medical and Natural Science, 6(4), 2112-2120. https://doi.org/10.51699/cajmns.v6i4.2940
Section
Articles