Evaluation of the Effectiveness of Polyoxidonium in the Treatment of Patients with Sinusitis with Benign Neoplasms of the Nose and Paranasal Sinuses
Keywords:
sinusitis, benign neoplasm, endotoxicosis, lipid peroxidation, polyoxidonium
Abstract
The paper presents the results of a study of endogenous intoxication in 68 patients with sinusitis with benign neoplasms of the nose and paranasal sinuses. Endogenous intoxication in this pathology is due to the accumulation of medium molecules in the plasma, activation of lipid peroxidation and a decrease in antioxidant protection. Polyoxidonium showed pronounced detoxification, antioxidant actions with correction of endotoxicosis indicators to control values.
References
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3. Galkin D.V., Krechikova O.I., Sukhorukova M.V., Dekhnich A.V. - Modern possibilities for the treatment of anaerobic infections.//Clinical microbiological antimicrobial chemotherapy.- 2006.- V.8.- No. 4 - р. 298-306.
4. Malakhova M.Ya. - Method of registration of endogenous intoxication: Methodical. recommendations. - St. Petersburg, 1995. -р. 33.
5. Mokhsen Ya.S., Belyaev A.N., Kozlov S.A., Baityakov V.V. - Pathogenetic correction of endotoxicosis in polypous rhinosinusitis. // International Journal of Applied and Fundamental Research.– 2010.- №1.- P.11-16.
6. Nikolaychik V.V., Moin V.M., Kirkovsky V.V., Mazur L.I., Lobacheva G.A. et al.-Method for determining "average molecules"//Lab.case.-1991.-No. 10.-р.
7. Safarova N.I., Karabaev H.E. - Polyoxidonium in the treatment of sinusitis in benign tumors of the nose and paranasal sinuses.//Stomatology. –2010. - No. 3-4. - р. 154-155.
8. Bair-Merritt M.H., Shah S.S., Zaoutis T.E., et al. - Suppurative intracranial complications of sinusitis in previously healthy children.//Ped. Infect. Dis. J.- 2005.- V.24.- N 4.- P. 384–388.
9. Hauptman G., Ryan M. W. - Otolaryngol Head surg. – 2007. - № 137(5). – P. 815.
10. Johanson L., Akerhund A., Holmberg K. // 3-rd international Consensus Conference on Nasal Polyposis. Abstracts book. - 2004. – P. 1.
Published
2023-06-18
How to Cite
U , L. G., I , S. N., & Kh, K. F. (2023). Evaluation of the Effectiveness of Polyoxidonium in the Treatment of Patients with Sinusitis with Benign Neoplasms of the Nose and Paranasal Sinuses. Central Asian Journal of Medical and Natural Science, 4(3), 1087-1091. https://doi.org/10.51699/cajmns.v4i3.1628
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