Современные Взгляды На Патогенетические Аспекты Синдрома Поликистозных Яичников У Женщин Репродуктивного Возраста. Современные Подходы К Выбору Диагностики И Лечения
Keywords:
синдром поликистозных яичников, яичники, гиперандрогения, метаболические нарушения, овуляция, инсулинорезистентность, бесплодие, ВРТ
Abstract
Синдром поликистозных яичников является одной из самых частых эндокринопатий у женщин репродуктивного возраста. Частота СПКЯ составляет около 30% среди пациенток гинекологов-эндокринологов, а в структуре эндокринного бесплодия достигает 75%. До 95% случаев гирсутизма у женщин связано с синдромом поликистозных яичников. Методы диагностики обширны и не ограничиваются только репродуктивной сферой. В статье представлены основные методы диагностики и стратегия лечения пациентов с СПКЯ.
References
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28. Cunha A, Póvoa AM. Infertility management in women with polycystic ovary syndrome: a review. Porto Biomed J. 2021 Jan 26;6(1):e116. doi: 10.1097/j.pbj.0000000000000116. PMID: 33532657; PMCID: PMC7846416.
29. Jain T, Negris O, Brown D, Galic I, Salimgaraev R, Zhaunova L. Characterization of polycystic ovary syndrome among Flo app users around the world. Reprod Biol Endocrinol. 2021;19(1):36. Published 2021 Mar 3. doi:10.1186/s12958-021-00719-y.
30. Teede HJ, Misso ML, Costello MF, et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril. 2018;110:364–379.
31. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, Piltonen T, Norman RJ; International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod. 2018 Sep 1;33(9):1602-1618. doi: 10.1093/humrep/dey256. Erratum in: Hum Reprod. 2019 Feb 1;34(2):388. PMID: 30052961; PMCID: PMC6112576
32. Pasquali R. Contemporary approaches to the management of polycystic ovary syndrome. Ther Adv Endocrinol Metab. 2018;9(4):123-134. doi:10.1177/2042018818756790.
33. Ахмедов А. Т., Особенности иммунной системы при врожденных пороков сердца, // EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE. – 2022. Vol. 2 No. 3 EJMMP. – С. 35-40
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2. Azziz R, Adashi EY. Stein and Leventhal: 80 years on. Am J Obstet Gynecol. 2016; 214:247. e1–247.e11.
3. Stein IF, Leventhal ML. Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol. 1935;29:181–191.
4. Khan MJ, Ullah A, Basit S. Genetic Basis of Polycystic Ovary Syndrome (PCOS): Current Perspectives. Appl Clin Genet. 2019 Dec 24;12:249-260. doi: 10.2147/TACG.S200341. PMID: 31920361; PMCID: PMC6935309. Kovanci E, Buster JE. Polycystic ovary syndrome. Clin Gynecol. 2015. Second Edition.
5. De Leo V, Musacchio MC, Cappelli V, Massaro MG, Morgante G, Petraglia F. Genetic, hormonal and metabolic aspects of PCOS: an update. Reprod Biol Endocrinol. 2016;14(1):38. Published 2016 Jul 16. doi:10.1186/s12958-016-0173-x/
6. Deswal R, Narwal V, Dang A, Pundir CS. The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review. J Hum Reprod Sci. 2020 Oct-Dec;13(4):261-271. doi: 10.4103/jhrs.JHRS_95_18. Epub 2020 Dec 28. PMID: 33627974; PMCID: PMC7879843.
7. Day F, Karaderi T, Jones MR, et all. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria. PLoS Genet. 2018 Dec 19;14(12):e1007813. doi: 10.1371/journal.pgen.1007813. Erratum in: PLoS Genet. 2019 Dec 5;15(12):e1008517. PMID: 30566500; PMCID: PMC6300389.
8. Franks S, McCarthy MI, Hardy K. Development of polycystic ovary syndrome: involvement of genetic and environmental factors. Int J Androl. 2006 Feb;29(1):278-85; discussion 286-90. doi: 10.1111/j.1365-2605.2005.00623.x. Epub 2005 Dec 22. PMID: 16390494.
9. Lewy VD, Danadian K, Witchel SF, Arslanian S. Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome. J. Pediatr. 2001;138:38–44. doi: 10.1067/mpd.2001.109603.
10. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004 Jan;81(1):19-25. doi: 10.1016/j.fertnstert.2003.10.004. PMID: 14711538.
11. Bruni V, Capozzi A, Lello S. The Role of Genetics, Epigenetics and Lifestyle in Polycystic Ovary Syndrome Development: the State of the Art. Reprod Sci. 2021 Mar 11. doi: 10.1007/s43032-021-00515-4. Epub ahead of print. PMID: 33709373.
12. Azziz R. Polycystic Ovary Syndrome. Obstet Gynecol. 2018 Aug;132(2):321-336. doi: 10.1097/AOG.0000000000002698. PMID: 29995717.
13. De Leo V, la Marca A, Petraglia F. Insulin-lowering agents in the management of polycystic ovary syndrome. Endocr Rev. 2003 Oct;24(5):633-67. doi: 10.1210/er.2002-0015. PMID: 14570747.
14. Rosenfield RL, Ehrmann DA. The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited. Endocr Rev. 2016;37(5):467-520. doi:10.1210/er.2015-1104/
15. Escobar-Morreale HF. Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment. Nat Rev Endocrinol. 2018;14:270–284.
16. Bremer AA, Miller WL. The serine phosphorylation hypothesis of polycystic ovary syndrome: a unifying mechanism of hyperandrogenemia and insulin resistance. Fertil Steril. 2008;89:1039–1048. doi: 10.1016/j.fertnstert.2008.02.091.
17. Hamilton-Fairley D, Taylor A. Anovulation. BMJ. 2003;327:546–549.
18. ESHRE Capri Workshop Group Health and fertility in World Health Organization group 2 anovulatory women. Hum Reprod Update. 2012;18:586–599.
19. National Collaborating Centre for Women’s and Children’s Health (UK). Fertility: Assessment and Treatment for People with Fertility Problems. London: Royal College of Obstetricians & Gynaecologists; 2013 Feb. PMID: 25340218.
20. Rees DA, Jenkins-Jones S, Morgan CL. Contemporary reproductive
21. Navruzova, Sh.I., Akhmedov, A.T. “"AUTOIMPLANTATION OF THYMUS IN SURGICAL CORRECTION OF CONGENITAL HEART DEFECTS." CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, - 2021. – Vol. 2.3 - (2021). – P.: 88-98.
22. Outcomes for patients with polycystic ovary syndrome: a retrospective observational study. J Clin Endocrinol Metab. 2016;101:1664–1672.
23. Bruyneel A, Catteau-Jonard S, Decanter C, et al. Polycystic ovary syndrome: what are the obstetrical risks? Gynecol Obstet Fertil. 2014;42:104–111.
24. Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R, Pfeifer M, Pignatelli D, Pugeat M, Yildiz BO; ESE PCOS Special Interest Group. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014 Oct;171(4):P1-29. doi: 10.1530/EJE-14-0253. Epub 2014 May 21. PMID: 24849517.
25. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004 Jan;81(1):19-25. doi: 10.1016/j.fertnstert.2003.10.004. PMID: 14711538.
26. Dewailly D. Diagnostic criteria for PCOS: Is there a need for a rethink? Best Pract Res Clin Obstet Gynaecol. 2016 Nov;37:5-11. doi: 10.1016/j.bpobgyn.2016.03.009. Epub 2016 Mar 31. PMID: 27151631.
27. Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES). American association of clinical endocrinologists, american college of endocrinology, and androgen excess and pcos society disease state clinical review: guide to the best practices in the evaluation and treatment of polycystic ovary syndrome--PART 1. Endocr Pract. 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855.
28. Cunha A, Póvoa AM. Infertility management in women with polycystic ovary syndrome: a review. Porto Biomed J. 2021 Jan 26;6(1):e116. doi: 10.1097/j.pbj.0000000000000116. PMID: 33532657; PMCID: PMC7846416.
29. Jain T, Negris O, Brown D, Galic I, Salimgaraev R, Zhaunova L. Characterization of polycystic ovary syndrome among Flo app users around the world. Reprod Biol Endocrinol. 2021;19(1):36. Published 2021 Mar 3. doi:10.1186/s12958-021-00719-y.
30. Teede HJ, Misso ML, Costello MF, et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril. 2018;110:364–379.
31. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, Piltonen T, Norman RJ; International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod. 2018 Sep 1;33(9):1602-1618. doi: 10.1093/humrep/dey256. Erratum in: Hum Reprod. 2019 Feb 1;34(2):388. PMID: 30052961; PMCID: PMC6112576
32. Pasquali R. Contemporary approaches to the management of polycystic ovary syndrome. Ther Adv Endocrinol Metab. 2018;9(4):123-134. doi:10.1177/2042018818756790.
33. Ахмедов А. Т., Особенности иммунной системы при врожденных пороков сердца, // EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE. – 2022. Vol. 2 No. 3 EJMMP. – С. 35-40
34. Ахмедов А. Т., Сравнительная оценка иммунологических параметров лабораторных животных аутоимплантации тимуса в динамике наблюдения, // EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE. – 2022. - Vol. 2 No. 3: EJMMP. C. 40-45
Published
2022-08-25
How to Cite
М. Х. , М., Г. А, И., Д. С. , И., & К. Т, Б. (2022). Современные Взгляды На Патогенетические Аспекты Синдрома Поликистозных Яичников У Женщин Репродуктивного Возраста. Современные Подходы К Выбору Диагностики И Лечения. Central Asian Journal of Medical and Natural Science, 3(4), 306-313. Retrieved from https://cajmns.casjournal.org/index.php/CAJMNS/article/view/1026
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